LM-3319FR 180204

Name	FR 180204
Synonyms	FR180204 FR 180204 LM-3319 FR 180204 ERK Inhibitor II, FR180204 5-(2-Phenylpyrazolo[1,5-a]pyridin-3-yl)-1H-pyrazolo[3,4-c]pyridazin-3-amine 1H-Pyrazolo[3,4-c]pyridazin-3-amine, 5-(2-phenylpyrazolo[1,5-a]pyridin-3-yl)- 5-(2-Phenyl-pyrazolo[1,5-a]pyridin-3-yl)-1H-pyrazolo[3,4-c]pyridazin-3-ylamine 5-(2-Phenyl-pyrazolo[1,5-a]pyridin-3-yl)-1H-pyrazolo[3,4-c]pyridazin-3-ylamine FR 180204
CAS	865362-74-9

Molecular Formula	C18H13N7
Molar Mass	327.34
Density	1.55±0.1 g/cm3(Predicted)
Melting Point	267 °C
Solubility	DMSO: ≥10mg/mL
Appearance	Yellow solid
Color	faint yellow to dark yellow
pKa	7.19±0.50(Predicted)
Storage Condition	2-8°C
In vitro study	In AP-1 transfected cells, FR 180204 dose-dependently inhibited AP-1 transactivation with an IC50 of 3.1 μm. FR 180204 inhibits spontaneous mesothelioma cell growth.
In vivo study	In mice with collagen-induced arthritis, FR180204 (100 mg/kg, I. P., B. I. d.) significantly reduced symptom progression and weight loss. In a mouse model injected with dengue Virus (DENV), FR180204 limits hepatocyte apoptosis, reduces DENV-induced liver injury, and improves clinical indicators.

Hazard Symbols	Xn - Harmful
Risk Codes	R22 - Harmful if swallowed R20 - Harmful by inhalation
WGK Germany	3
HS Code	29339900

Last Update：2024-01-02 23:10:35

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Product Name: FR 180204 Visit Supplier Webpage Request for quotation
CAS: 865362-74-9
Tel: 18301782025
Email: 3008007409@qq.com
Mobile: 18021002903
QQ: 3008007409

Wechat: 18301782025

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LM-3319FR 180204

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